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What is the Dietary Inflammatory Index (DII)?

Inflammation is a normal biological process involved in the body's response to injury and infection. Persistent low-grade inflammation, however, has been associated with several chronic conditions, including cardiovascular disease.

The Dietary Inflammatory Index (DII) is a widely accepted, validated dietary index that estimates the inflammatory potential of an individual's overall diet. It is calculated using dietary components that have been studied for their relationships with inflammatory markers.

When the DII is adjusted for energy intake, it is expressed as the Energy-Adjusted Dietary Inflammatory Index (E-DII).

How Does It Work?

DII and E-DII values describe the inflammatory potential of the overall dietary intake rather than the inflammatory effect of a single food.

The index is useful for evaluating the overall dietary pattern and for comparing changes in dietary inflammatory potential over time.

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It should not be interpreted as a clinical diagnosis or as a direct measure of inflammation in the body itself.

+5 Higher inflammatory potential
+2 Moderately elevated
0 Neutral midpoint
−2 Lower inflammatory potential
−5 More anti-inflammatory
Pro-inflammatory Anti-inflammatory
Higher values More pro-inflammatory dietary pattern

Higher DII or E-DII values reflect an overall pattern with greater estimated inflammatory potential.

Lower / more negative values Lower estimated inflammatory potential

Lower or more negative values indicate an overall pattern with lower estimated inflammatory potential.

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Meal Combination Energy
(kcal)
Protein
(g)
Carbs
(g)
Fat
(g)
E-DII
Validated dietary index that estimates the inflammatory potential of an individual's overall diet.
108 5.3 7.6 6.8 -2.32
107 5.37 7.5 6.8 -2.32
116 4.5 6.5 8.6 -1.63
37 2.7 4.7 0.8 -0.74
10 0.2 2.8 0.05 -1.97
Meal Combination Energy
(kcal)
Protein
(g)
Carbs
(g)
Fat
(g)
E-DII
Validated dietary index that estimates the inflammatory potential of an individual's overall diet.
302 15.9 43.1 7.8 -2.66
353 16 43.3 13.3 -3.09
310 11.9 49.7 7.8 -2.72
375 17.6 64.5 7.3 -4.64
357 14.6 61.3 8.1 -3.58
380 22.5 51.9 10.4 -7.02
220 15.4 34.2 2.6 -2.6
221 13.1 35.7 3.4 -2.69
405 21.4 68.3 7.4 -5.56
407 19 69.7 8.2 -5.6
425 19.7 68.8 9 -5.1
Meal Combination Energy
(kcal)
Protein
(g)
Carbs
(g)
Fat
(g)
E-DII
Validated dietary index that estimates the inflammatory potential of an individual's overall diet.
148 2.1 20.1 8 -2.47
191 8.4 25.2 7.9 -4.61
133 2.8 15.4 7.9 -4.34
180 3.4 23.9 9.6 -3.77
148 2.7 19.3 8.05 -2.4
148 2.7 19.3 8.05 -2.4